Since two of the choices are smaller guns I'm definitely not going to go with others and say a Glock (I'm not a Glockite anyway). But really if you are familiar with and comfortable with a .45 I would definitely get the XDs.
Myself, I don't own a .45, and probably never will, so I would go with something else like a Sig P238, P938 or P290. But, if you are comfortable with a .45 definitely go with the biggest caliber you can (within reason).
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