I don't have direct experience with a 1:10 twist .22-250, but maybe this will give you some ideas.
I have a Remington 700 in .22-250 with 26 inch barrel with a 1:14 twist.
It shoots 40 grain to 52 grain bullets exceptionally and shoots 55 grain bullets almost as well. It also shoots 35 grain bullets well but it shoots the 40-52 bullets best. Accuracy drops off with bullets that are heavier than 55 grains.
A buddy has a new Savage 12 with a 1:12 twist that shoots 52 grain bullets exceptionally. It is so new that he hasn't tried 40 grain or 55 grain bullets yet.
I suspect it will shoot the 55s more accurately than my Remington and might shoot up to 65s accurately with the faster 1:12 twist.
I would expect that your 1:10 twist would shoot bullets of 55 grains and above better than the 50 grain V-Max. I would expect it to shoot the V-Max ok but you might have issues with over stabiliztion if you shoot it near max velocities. I expect that a 1:10 would shoot 75 to 77 grain bullets accurately and might even shoot 80 grain bullets accurately.
Let us know how your experiments turn out.
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