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I've shot 1000s of rounds from my 7 1/2" Redhawk and taken sveveral whitetails with it.
22.5-24.5 H110 or W296 will get you around 1400 fps with excellent accurracy. These work best for top end magnum loads. Use magnum primers with these powders. Blue Dot wasn't bad, but inferior to these two. Its better for moderate mag traget loads. I also use Unique whcih works fine for cast bullet light mag target loads, but nowhere near the accurracy and performance in jacketed hunting loads.
Hornady XTP is an excellent bullet, and 240gr is the best choice. I tried some 300gr and they shoot so high that if I sight them in, I won't be able to shoot anything else. My best group was 7" at 100 yards with iron sights with 240gr in front of 24.7gr 296.
Also, what gun are you shooting these in? Rugers tend to be able to digest loads that other guns can't handle. 24.7gr was max listed charge, but I've loaded 240gr cast bullets as high as 26.5gr H110. I wouldnt shoot those in a S&W though.
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