I have a Weatherby Mark 5 Predator Master and with Hornady V-Max 55gr it's a deadly and accurate combo but if the winds blowing and the shot is over 150yds I reach for the Sako 22-250 SS Varmint shooting 55gr Hornady V-Max. With all that pasture it sounds like you will have the oportunity to take some long shots so the 22-250 or the 243 would be better IMO.