I believe L Killkenny is correct about the bottle neck cartridge in revolvers.
It seems that I recall it being tried before and the bottle neck cartridge wants to back out of it's cyclinder chamber and tie the gun up.
Also the point WeedWacker made about reloading would be another thing many would not want to contend with when it comes to revolver ammo.
Now in a rifle it might be something fun to play with.
Best Regards
Bob Hunter
www.huntercustoms.com