Just to be clear, are you talking about the Auto-Ordnance M1 semi auto??
and, if so, is the receiver steel??? The "lightweight" models (listed at about one pound lighter weight) used Aluminum alloy though I don't know remember if it was the upper, the lower, or both.
If your upper isn't steel, that could be why the screws don't stay tight.
I have one of the deluxe 1927A1s, all steel and wood. Never had any issues with anything coming loose.
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All else being equal (and it almost never is) bigger bullets tend to work better.
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