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Driftwood, i can +1 that. Huge size, huge weight, big recoil to get decent defensive loads. Naw, make mine a 40 or 45!
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Big +2 I'd much rather have my 21ozCharter Bulldog and a few CCI shot capsules.
I had a 45 colt 410 contender barrel and without the choke it was marginally more effective than 44 or 45 shotshells.