Yes.. seating to the center of the cannelure is good. If you decide to put a slight roll crimp on it, it gives the case mouth somewhere to go. I'm not sure I'd worry much about a crimp, with as little recoil as these loads will have.
Seating depth is one of those variables that you can play with to fine tune your load. Seating the bullet flush with the mouth might work better, but the only way you will know is to shoot a bunch of them.
It's a tough job...