I've owned and shot deer with both the 243 and 358, I don't like either one of them for deer hunting here in Colorado but if I had to choose it would be the 358, bigger holes are always better.
I believe I've killed over 225 big game animals in Colorado, Wyoming and Kansas.
Mostly deer and antelope with just about everything you can imagine, pistols, vertical compound and crossbow and many different cartridges from rifles.
I like a minimum 6.5 caliber with a 140gr. bullet, a 7-08 with a 140gr. bullet being my favorite. Those bullets kill even big deer very fast without alot of meat damage.
My wife has this knack for shooting wallhangers, she killed this one last year with her model 7 remington 7-08 with one shot, he went about 10 feet.
