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.45 Long Colt vs. .45 Colt is always two different names applied to the same thing.
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Which is why pedantic debates over useage is counter productive.
Back to the real topic. .45 colt is a lousy self defense caliber. Yes, I said it.
It might destroy more tissue than other rounds, but its size and weight do not allow for firearms that are easily concealed or carry decent quantities of ammunition.
I would much prefer 10 rounds of 9mm to 6 of .45, especially when the 9mm options are cheaper, lighter weight, flatter, easier to reload, etc...