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Barnes' bullets should not be loaded with any other data but what has been developed specifically for them. Use a powder that they have developed data with and follow their recipes. Also, 45 +P brass generally has smaller internal capacities than standard brass and this will make a difference. If Barnes isn't using +P brass I wouldn't either. If you do use it definitely don't load to their max charges. I've used quite a few powders in 45 auto and like N320 and Universal because they are clean and accurate. Bullseye is the old standby in this caliber but it is too dirty for my tastes, but it sure is accurate. I've never seen anything to be gained by using powders slower than Unique or Universal in 45 auto and the faster powders will do everything that needs doing in this cartridge and will do it with less powder. W231/HP38 is a good choice too, if Barnes has data with it.
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