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"...any pistol load really need..." Depends entirely on the powder used.
Using a magnum primer might increase your pressures, but it will not cause any damage to anything.
4.8 - 5.8 grains of Unique is a jacketed bullet load, not for cast, coated or plated bullets. 4.8 isn't the right start load either. Alliant shows the Max load is 5.8 for a 124 grain bullet(one grain doesn't matter). 10% reduction is 5.2. That OAL is too short too. 1.169" works with any bullet weight. Been using that for eons with a cast 121 grain TC.
H110 usually does not require magnum primers.
"...will have a harder cup..." No they don't.
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