Depends. If you have an open top, I always break it down and throw the barrel, cylinder into a bucket of soapy water. Then use a blackpowder solvent on the frame. On a Remmy I soak the cylinder and use solvent on the frame and barrel. You could take off the grips and soak the frame too, but usually I wait awhile to do that. I am sure you will get alot of tips in this forum.
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