If regular handgun ammo was simply not available and I had to
opt for something like this, I would go the route of the Winchester PDX1 ammo.
My in-laws keep this in a S&W Governor in their bedroom for home defense. My personal experience shooting it at the range, the disks easily hold close enough together that nothing will miss a body-sized target when aiming at center mass.
"We believe that all men are justified in defending themselves, their friends, and property, and the government, from the unlawful assaults and encroachments of all persons in times of exigency, where immediate appeal cannot be made to the laws, and relief afforded."
~Doctrine and Covenants 134:11