My uncle was a Ft Worth cop and killed one man while on duty. He killed him with the standard issue 158gr LRN given to cops in the mid to late sixties. He used a model 15 and killed the guy with one shot. He dropped right where he stood.
A LRN would not be my first pick but if its what I had and needed it right then you can bet I would use it. But I would prefer almost any other bullet shape for SD.
If you can find a box of Sellier&Bellot 158gr RNL pick up a box. This stuff is loaded hot. IIRC they list it on their site as getting 960fps and I beleive them. And it is NOT listed as +P ammo. I do wish it would occur to them to load some 158gr lead hollow points to the same velocity.