In .38 Special with 158 grain cast bullets, I use 4.5 grains of Unique for a normal load, and 4.5 grains of American Select for a +P load. I also shoot a lot of 148 grain wadcutters using 2.6 grains of Red Dot.
In .357 with 158's I use 8.0 grains of Herco. If I want to go hotter, I switch to AA#7 (don't remember the amount, it's about 10 or 11 grains.) 148 grain wadcutters with 4.5 grains of Red Dot is a fun load and very accurate.
"The only way to stop a bad guy with a gun is with a good guy with a gun"