I don't load for a 25-06 but looking at Hodgdon data with H-1000 and Retumbo with the heavier bullets your using on average 3/4more grains of powder compare to others at same velocity. If I was going to use mag primer I might look at other powders. It kind of the same with the 270 and Retumbo.
Since I load at the range one option I can change primers on load development and most time I see no difference in accuracy on rifles I decide to switch primers. My 280AI and 35 WhelenAI I'd seen better accuracy and when I chronograph got small increase in velocity and primers I used was Fed 210M and Fed 215M.
Well good luck
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