Two different ways
I ride a Fat Boy and I carry two different ways when I am riding. I have a concealed carry vest that can carry a pistol on each side. I try to carry two when I wear it so that it balances out weight wise.
I also carry IWB sometimes. The first few times I was checking often to make sure the gun was not creeping out of the holster, but after that I was confident enough that it was secure that I have no concerns with that method now. I guess the confidence level would depend on the holster you are using.
There is only one good, knowledge, and one evil, ignorance.