The way I figger, I try to hit them in the neck where there's plenty of juices to let the hydrostatic shock to do the dirty work. 'cept that when the eyes pop out, it gives me the Willies. Sometimes a 45 to the head is not as speedy.
With coyotes any Varmint round to the fuselage is usually instant incapacitations.
But, now the disclaimer: I base my facts on my own theory of the facts, not on any real facts, and can't be proven by any reasonable means