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Do you have hardness for those bullets?
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Do you have a thumbnail?
While having a good hardness rating is fine, the "rule of thumb" also works. Try to notch the base of the bullet with your thumbnail. If you leave a bright mark (or no mark) the bullet will be good to 1000fps or maybe more, without leading. IF you can gouge out a small divot in the lead, keep the speed low, 850fps, or so.
I have been loading 10.0gr Unique under a 250gr bullet (usually SWC, but sometimes RNFP) for 27 years. My Blackhawks like it. I like it. And while there are probably cleaner powders out there today, I'm not changing. CLocks 1070fps avg from my 7.5" barrel.
Hits hard, and recoil is not painful. And did I mention accurate? I can ring the 200yd gong on the rifle range, all day long.