I live in a 2-story home with all bedrooms on the 2nd story. There is also a basement with its own door and 4 windows. I have a couple of kids who are usually off to college. Their bedrooms are in between my bedroom (at the end of the hall) and the top of the stairs.
I have an alarm system (which I'm sure could be defeated, but probably not by anyone who might be primarily desiring to inflict injury on the family) on all doors and windows on the basement and first floor levels, and also a watch-cat that is probably somewhat less than reliable
If the kids are away I would certainly not charge down the hall to face an intruder. However, if they are home, I would have no choice but to get down that hall to their rooms asap.