If it functions for 40-50 rounds OK, then the problem is most likely a buildup of powder fouling or bullet lube in the action, especially around and under the extractor, and in the extractor slot in the barrel. A Model 41 is closely fitted, but it should go several hundred rounds without a problem.
How many kinds of target ammo have you tried? There is a tendency to label every cheap store brand of ammo as "target" ammo, even if it won't shoot for beans.
If you want to use "target" ammo, buy the good stuff (RWS, Ely, Federal) and pay the piper. Otherwise, if the gun shoots with the High Speed ammo, use it. That is not a plinking gun for use with cheap ammo; it deserves the best.
BTW, mine shoots superbly with Remington "golden bullet" high speed.
Jim
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