.....45gr of Pyrodex P behind a .454RB or hand cast Lee conical. The RB's are tighter grouping, but the punch of the conicals launched with 45gr P is astounding. Steel gongs that rock and sway when shot with a RB jerk and jump when pranged with the Lee.
This load, unfortunately, is just strong enough to drop the loading lever almost every time.
Anything over that just wastes powder, and accuracy suffers.
Some guys just twist one of those ladies stretchy hair elastic thingies or a rubber band around the barrel/loading lever to combat the LL drop.
Being a 'real man', I just deal with it.....LOL!