Giz said it when it comes to shot placement. I guess this goes with do as I say not as I do
but I have dropped em in their tracks with a heart/lung shot with the Speer 70 grain semi spitzer in my 22-250. These were river bottom deer with some going near 200#, not the marsh deer where a big one is 125#. Now this was rye grass field shooting, if it was in the woods, or ahead of the dogs then its time for an 06 or something along that line.