No, I don't think so, but maybe. I think the entire point here is what is THE most ethical shot. ML bullets - even conical ones from a powerful inline - often don't make an exit hole that bleeds - elk are notorious for sealing up the offside wound and never being found, in my understanding - THAT is unethical - not using enough gun and wounding an animal, or killing but not recovering. So if you're "hampered" with technology that doesn't have the same chance of a GOOD exit hole, it makes sense to hit CNS, carotid, jugular, and trachea in one explosive devastating shot instead. But I dunno for sure; that's why I'm asking. Just my guess.
Now if the answer is "use a .54 or .58 with a 400+ bullet, instead of a .50, and you will get a good exit hole nearly every time", then maybe that's the answer to the perceived problem rather than neck shots. But Mobuck, I will take your opinion under advisement under the "no" column, if you've hunted them.