[m&p45acp10+1]

If you have a volumetric powder measure it should meter the powder just fine. My Lee Perfect Powder Measure will drop charges of it right on the money every time. Just make sure you do not double charge your cases.

As a note what kind of press, and measure are you using?

If a single stage then put the empty, primed, flared brass in a bowl with an empty loading block near. Once you have your powder measure set up to throw the charge you want take a case out. Turn it upside down, and put it into your powder funnel. Now put it upright, and under the powder measure. Work the handle to dispense the powder. Put the case in the block. Repeat till all in the block are charged. If you want to be extra careful then weigh every 5 to 10 charges. When the block is full look into every case to be sure there is powder in them all, and that none look like they have way more powder inside than the others. After checking that start seating bullets.