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What I can say is that once a given round hits the human body, the amount of energy in that round determines the amount of damage it can do.
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Not even close, at least as far as this discussion of 45 vs. 9mm. Neither cartridge has "energy" capable of inflicting serious trauma (ie hydrostatic shock). The trauma inflicted upon the human body by a 9mm or .45 handgun bullet is determined by the structures which are cut and torn by the bullet itself.