Mr. Smith nailed it....as usual
While I certainly want everyone to feel safe with their chosen sidearm
A whole lot can go wrong in the process of chambering a round
In addition to those obstacles listed, I would add the possibility that some pesky article of clothing could find its way into a bad place.
At contact distances a pistol without a round chambered will likely be employed as an impact weapon only...if it is not dropped during all that manuevering
In cases like that you would probably be better served with a good knife than an unloaded gun