There are times when all I can get away with carrying is my Ruger LCP. I have XXL hands and the Ruger LCP does really well for me. I put a Hogue rubber grip and bought some sight paint to make the front post (more like a nub) more visible.
As the old saying goes, better a pocket full of bullets in a gun you are carrying, than a bunch of .45ACP back home.
Here's a video on how the Ruger LCP does for me:
http://www.youtube.com/watch?v=tvV3DGJkyRk