What bullet are you describing as a 180 SBT?
Bullet choice is your only factor in using the 300Wby. I'd suggest something with a controlled expansion feature to prevent over expansion. While bears may be of similar weight to deer, their build and bone structure is different and probably requires some attention in bullet selection. I'd lean toward an "elk" type bullet. The bears I've killed or seen killed were at close range with 30/06 using 180 grain Hornady interlocks and 12 gauge "forster" type slugs. Both types of projectiles produced one shot kills and complete penetration on 150-250# bears.
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