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If you buy 44/40 cases they have to be made to use in any 44/40 so they are loaded to traditional levels but with the new case and heat treated steel frame and cylinder you opught to be able to increase the performance on a 44/40- the question is...by how much and still be safe?
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The case necks are still very thin and will not hold up to very many heavy charges.
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I finished loading a hundred rounds with 25 grains (by weight) of 777. Haven't shot any yet. That much powder in .45 LC gives me a lot of recoil.
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You like living dangerously huh Doc.