The perfect "Grandma Gun":
http://www.impactguns.com/store/86B210.html
Almost 24 oz. empty, and chambered in .380=very little recoil
Tip up barrel=not having to wrestle with the slide if you don't want to. (Though that is not difficult if Grandma knows what she is doing ..... and the Cornered Cat 'splains it pretty well if she does not:
http://www.corneredcat.com/RunGun/rack.aspx