TrailBoss is has even lower bulk density than SR4759. From Lee's VMD chart, SR4759 is 0.653 grams/cc. Trail Boss is just 0.298 grams/cc, so it takes up a little over twice as much space per gain. It's got the lowest bulk density of any powder on Lee's list. It burns fast, like a pistol powder, but you can't fit enough in to damage a modern rifle. That means the velocity it produces is limited. It's only hazard is you can't compress it at all without risking pressure spikes.
The IMR load
Trail Boss instructions are here.