We're taking about handloads now
?
Man, I'm out of it for a bit and everyone gets delusions of grandeur
.
Seriously though, use what you like best. The 45 has been killing people longer, but the 40 has been working hard to kill people too. I personally wouldn't want to be shot with either. Come to think of it, I'm not sure I would really care which you shot me with. I'd probably be pretty irate either way.