The Uberti can handle much more than 20, grains, and you'll probably get better groups with more powder. But the 8" drop is definitely sight alignment. There's no way a .375 or .380 round ball propelled by 20 grains of black powder drops 8" in 25 yards.
Frankly, I think your .44 needs sight work also. A 1" drop in 25 yards is also excessive.
You should be evaluating gun performance based on group center rather than individual round location. If your (minimum of 3 rounds each) groups are 1" below point of aim, then you have something you can work with.
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