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Start with the .30-06 and research from there. It has the most available commercial loads. Ammo can be found anywhere. Does everything that needs doing in North America and a good portion of Africa without brain-bouncing recoil.
If you think you need more power, Federal High Energy and Hornady Light Magnums turn the '06 into a .300 H&H. If you handload you can reach this level easily and safely.
The rifle.....that's up to you. Get what fits and works for ya.
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