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Owning both and hunting with the 10mm. The 10mm blows the 45acp away in ever aspect. Even with super hot 45acp, they just don't penetrate like the 10mm. The 45acp at best, is a marginal whitetail round. I have killed many deer with the 45 Long Colt and it is where you want to start if you want a 45 caliber. I do like the hot 200 grain 45acp Corbon rounds for self protection and as a woods gun.
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