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Back when I did the cancer dance, and they installed that infernal Groshong Catheter, I made sure it was installed in the left upper chest area so I could shoot. (Right handed)
They removed all the axilla lymph nodes under the right armpit, so I can relate to her discomfort. It took a long while to stretch out that area there doing those "spider crawl" hand exercises on the wall, but in time the pain and discomfort diminished.
After a long while, maybe a year and a half or so, I was able to shoot without discomfort, including steel buttplate Sharps rifle in BPCR.
I do not know how long your wife has been since the surgery, but a year or two later she will no longer have discomfort there, if she does those stretching exercises, and probably be able to shoot whatever she wants to shoot. At least that is my experience.
I cannot comment on the area where the breasts were removed. If she places the butt in the pocket probably it won't bother her after a time.
Hope this helps, and you have my sympathies.
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