I've been shooting 41's for almost 20 yrs and the 1 load that I've shot more of than any is 20gr H110,Federal primer and Nosler 210 gr HP. Had a Blackhawk once that preferred Blue Dot,don't recall the charge however.My 45 Colt loads have used H4227(some unburned powder,but a good load) Unique and Universal Clays all use either 255 SWC or 250 jacketed HP. Swifter, I agree 1000% these 2 along with ACP round are my favorites !
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