I usually load only quality (say, Cor-Bon) JHP in a CCW figuring it's for flight, not fight. Point being, score a center-mass hit or two if necessary and bug out. That's me, but I can see a LEO or other reasons for mixing. Although:
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Mixing ammo in a mag is an open invitation for feeding issues IMHO.
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... I don't think the gun remembers what the last round was when reloading...