The trick to long range shooting of any handgun is (for me) not aiming above the target, but holding up the front sight, with the target on top of it.
I can regularly hit the 200yd gong at my local range with my 7.5" .45 Colt Blackhawk, and with a few sighter shots, any other handgun you care to name, and this I do, offhand, one handed.
All one needs is a little skill, some practice (in my case, only about 35 years or so), and a suitable sandy backdrop to spot the shots. Once you learn how much drop to compensate for, at any given distance, it doesn't change. Then all you have to allow for is the wind!
Doing it from a rested position just makes it easier!
Yes, you are pointing the pistol pretty well up in the air for really long shots, but thats just the nature of the physics involved. Think "howitzer".
