I have always been a fan of the 22 Hornet. It's like shooting a .22LR but with a lot more power at the business end.
I had a little Martini Cadet rechambered for that round and I have used it on varmint with very good success.
But there is nothing wrong with a 222, 223, 22-250, 17, 25-06 or 22 Bee for that matter. Use what speaks to you.
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