Why the 40??? Its more powerful than a 9mm and holds more than a 45acp. I have killed deer very efficiently with my 10mm loaded to hot 40 spec. I wouldn't hunt deer with any 9mm or 45acp. If money is no object, then the Sig Sauer P229 is a purpose built 40s&w. They are extremely accurate. Out of my 27 handgun collection of multiple calibers, my P229 Elite Dark in 40s&w is my number one choice as a bed side gun. I have had it to Gunsite and it has never malfunctioned with any ammo.
This is full power Critical Defence in 40 with 500 ftlbs of energy rapid fire.