If you carry a loaded cylinder (say in a pouch, on its side) wouldn't the powder flow out of the nipple holes as you walk/move about? then you would end up with some powder in your pouch, eating the leather? If the pouch holds the cylinder upright, moisture might get in and dampen the powder in the nipple and may cause a FTF? I always keep my ROA's capped at the range, but the hammer in one of the safe slots between chambers. Carrying an uncapped cylinder would worry me, both for powder coming out & moisture getting in? I would be capping them if I were ever to carry a spare cylinder (which I dont), but thats just my opinion
Like I said before, to drop a loaded capped cylinder on something hard enough, precicely enough to get it to fire would be difficult (but I agree, not unheard of)