+1 on trying a slower burning powder. With the 158gr, I have had great success with Unique and Herco in .38s and 2400 and H110 out of the magnums. I have never had success with Bullseye in anything other than light loads.
The slower powders excel in the longer barrel lengths of handguns, providing a good push rather than a quick slap to the back of your bullet.
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