I think I tried about 20 - 25 different combinations, between types of powder, amounts of powder, bullets and bullet seating depths to find the magic load for my .308!
rwilson452 is right, you need one of those sweet little electronic powder measure machines, they're fast and easy, and you get a very accurate powder weight each time.
The powder measure on the Dillon 550 that I've got is not real accurate and it's messy, it spills a little powder with each load when I load rifle calibers. But it's great for the 45 ACP and other hand gun calibers..
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