I like 2400 with 240 grn slugs. Its alot mor forgiving than H110 or 296. 18 grns behind a 240 is a good starting point and 22 grns is a good max in my redhawk. H110 and 296 are great powders but they only have 1 to 2 grns between start and max, so they may be a bit much for target shooting. Just remember not to reduce these two powders more than the book sais and use mag primers with them. Oh, and a heavy crimp.
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