I used a Hornady 125 gr SST over 18.5 grains of Lil Gun to take a 100 pound whitetail doe, the range was 154 yards. The round appeared to expand well,
Leaving a basketball sized hematoma in the impact side rib age, and a golf ball sized exit through the shoulder blade. The deer ran about 50yards. My only problem was that I hit her high and she didn't leave a blood trail for around 15 yards. Once the blood trail was found, it was easy to follow.
I like the 300, and look forward to hunting with it next year.
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