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I loved my .22-250 and while I found the 60 grain Hornady bullets didn't shoot especially well in my Remington (1 1/2 minute groups), they didn't keyhole. The 60 grain Nosler Partitions are a bit shorter and may be fine.
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That's not a bad group at all if you are gonna shoot a deer. That would even be ok for woodchucks out past 200 yards.