The sabot .45 bullets may not have grease or lube rings on them. If not they will lead up your barrel something fierce!
Also they may not load straight going down the barrel.
AND, you want to measure the OD to see if they're the fight sizr for your bore. If they are .440" they should be OK.
If they are long enough with lube rings on them,lube them up and shoot them!!
Be sure to but a button under them over the powder or fill the base of the bullet with lube if it is a hollow base bullet.You don't want a air pocket between the powder and the bullet!